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Predictors of long intensive care need after lung transplantation.
Olsen, Jul Eirik; Auråen, Henrik; Durheim, Michael T; Fiane, Arnt E; Holm, Are M.
Afiliação
  • Olsen JE; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
  • Auråen H; Department of Gastroenterological Surgery, Oslo University Hospital, Ullevål, Oslo, Norway.
  • Durheim MT; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
  • Fiane AE; Department of Respiratory Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
  • Holm AM; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Clin Transplant ; 35(1): e14152, 2021 01.
Article em En | MEDLINE | ID: mdl-33185913
BACKGROUND: While expected need for intensive care after lung transplantation (LTx) does not normally affect organ allocation, it would be useful to estimate whether intensive care capacity is limited. The aim of this study was to assess factors available before LTx to identify predictors of prolonged intensive care unit (ICU) length of stay (LOS) after LTx. METHODS: All bilateral LTx recipients excluding re-transplantation and multi-organ transplantation at Oslo University Hospital from 2000 to 2013 were included (n = 277). Predictive factors for ICU LOS were identified using pre- and perioperative variables. RESULTS: Univariate analyses showed that recipients with pulmonary arterial hypertension, young age, female gender, low body height, low pretransplant actual total lung capacity (aTLC), and recipients who received an oversized donor lung were at risk for long ICU LOS. Patients with emphysema had lower risk of long ICU LOS. In multivariate analyses, a lower aTLC (p < .001) and a higher mean pulmonary artery pressure (mPAP) (p = .004) predicted prolonged ICU LOS. CONCLUSIONS: We found that small recipient lung volume and high mPAP were predictors for prolonged ICU LOS. Our observations may be useful in planning use of resources in LTx, particularly in times of limited intensive care resources.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pulmão Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Clin Transplant Assunto da revista: TRANSPLANTE Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Noruega País de publicação: Dinamarca

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pulmão Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Clin Transplant Assunto da revista: TRANSPLANTE Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Noruega País de publicação: Dinamarca