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Flubendazole, FDA-approved anthelmintic, elicits valid antitumor effects by targeting P53 and promoting ferroptosis in castration-resistant prostate cancer.
Zhou, Xumin; Zou, Libin; Chen, Wenbin; Yang, Taowei; Luo, Junqi; Wu, Kaihui; Shu, Fangpeng; Tan, Xiao; Yang, Yu; Cen, Shengren; Li, Chuanyin; Mao, Xiangming.
Afiliação
  • Zhou X; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China; Department of Pathogen Biology and Experimental Teaching Center of Preventive Medicine, Guangdong Provincial Key Laboratory of Tropical Disease, School of Public Health, Southern Medical University, Gu
  • Zou L; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Chen W; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Yang T; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Luo J; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Wu K; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Shu F; Department of Urology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou 510623, PR China.
  • Tan X; Department of Urology, The First Affiliated Hospital, Southwest Medical University, Luzhou 646000, PR China.
  • Yang Y; Department of Urology, Peking University Shenzhen Hospital, Shenzhen 518036, PR China.
  • Cen S; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China.
  • Li C; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China. Electronic address: li-chuanyin@163.com.
  • Mao X; Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou 510280, PR China. Electronic address: mxm@smu.edu.cn.
Pharmacol Res ; 164: 105305, 2021 02.
Article em En | MEDLINE | ID: mdl-33197601
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias de Próstata Resistentes à Castração / Ferroptose / Mebendazol / Anti-Helmínticos / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Guam País de publicação: Holanda
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Supressora de Tumor p53 / Neoplasias de Próstata Resistentes à Castração / Ferroptose / Mebendazol / Anti-Helmínticos / Antineoplásicos Limite: Animals / Humans / Male Idioma: En Revista: Pharmacol Res Assunto da revista: FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Guam País de publicação: Holanda