USP10 deletion inhibits macrophage-derived foam cell formation and cellular-oxidized low density lipoprotein uptake by promoting the degradation of CD36.

Xia, Xiaohong; Hu, Tumei; He, Jinchan; Xu, Qiong; Yu, Cuifu; Liu, Xiaolin; Shao, Zhenlong; Liao, Yuning; Huang, Hongbiao; Liu, Ningning

Xia, Xiaohong; Hu, Tumei; He, Jinchan; Xu, Qiong; Yu, Cuifu; Liu, Xiaolin; Shao, Zhenlong; Liao, Yuning; Huang, Hongbiao; Liu, Ningning.

Afiliação

Xia X; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Hu T; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
He J; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Xu Q; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Yu C; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liu X; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Shao Z; Guangzhou Institute of Cardiovascular Disease, Guangdong Key Laboratory of Vascular Diseases, State Key Laboratory of Respiratory Disease, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Liao Y; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Huang H; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.
Liu N; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Protein Modification and Degradation, School of Basic Medical Sciences, Guangzhou Medical University, Guangzhou, China.

Aging (Albany NY) ; 12(22): 22892-22905, 2020 11 10.

Article em En | MEDLINE | ID: mdl-33197885

Assuntos

Antígenos CD36/metabolismo; Células Espumosas/enzimologia; Lipoproteínas LDL/metabolismo; Macrófagos/enzimologia; Ubiquitina Tiolesterase/metabolismo; Linhagem Celular; Humanos; Ubiquitina Tiolesterase/genética

Palavras-chave

CD36; USP10; atherosclerosis; degradation; foam cell

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígenos CD36 / Ubiquitina Tiolesterase / Células Espumosas / Lipoproteínas LDL / Macrófagos Limite: Humans Idioma: En Revista: Aging (Albany NY) Assunto da revista: GERIATRIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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