Ocular Sparganosis: The First Report of Spirometra ranarum in Thailand.
Korean J Parasitol
; 58(5): 577-581, 2020 Oct.
Article
em En
| MEDLINE
| ID: mdl-33202511
ABSTRACT
A 22-year-old Thai man from the Northeast region presented with acute eye swelling, itching, and discharge on his left eye. He was suspected of having gnathostomiasis and treated with albendazole and prednisolone for 3 weeks. Nine months later, he was treated with high-dose oral prednisolone for the preliminary and differential diagnoses with thyroid-associated orbitopathy and lymphoma. He had been administered prednisolone intermittently over a few years. Then he developed a painless movable mass at the left upper eyelid and recurrent pseudotumor oculi was suspected. The surgical removal of the mass was performed. A white pseudosegmented worm revealed a definite diagnosis of ocular sparganosis by a plerocercoid larva. Molecular diagnosis of the causative species was made based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Proper technique of extraction and amplification of short fragments DNA from formalin-fixed paraffin-embedded tissue successfully identified parasite species. The result from the sequencing of the PCR-amplified cox1 fragments in this study showed 99.0% sequence homology to Spirometra ranarum. This is the first report of S. ranarum in Thailand.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plerocercoide
/
Spirometra
/
Esparganose
/
Olho
/
Oftalmopatias
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Adult
/
Animals
/
Humans
/
Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Korean J Parasitol
Assunto da revista:
PARASITOLOGIA
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Tailândia