NMIIA promotes tumorigenesis and prevents chemosensitivity in colorectal cancer by activating AMPK/mTOR pathway.

Wang, Zhong; Zhu, Zhanyong; Li, Chenyuan; Zhang, Yimin; Li, Zhiyu; Sun, Shengrong

Wang, Zhong; Zhu, Zhanyong; Li, Chenyuan; Zhang, Yimin; Li, Zhiyu; Sun, Shengrong.

Afiliação

Wang Z; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Zhu Z; Department of Plastic Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Li C; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China.
Zhang Y; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China. Electronic address: dryiminzhang@163.com.
Li Z; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China. Electronic address: lizhiyu@whu.edu.cn.
Sun S; Department of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan, Hubei, PR China. Electronic address: sun137@sina.com.

Exp Cell Res ; 398(1): 112387, 2021 01 01.

Article em En | MEDLINE | ID: mdl-33220257

Assuntos

Proteínas Quinases Ativadas por AMP/metabolismo; Neoplasias Colorretais/metabolismo; Cadeias Pesadas de Miosina/metabolismo; Serina-Treonina Quinases TOR/metabolismo; Idoso; Animais; Apoptose; Proliferação de Células; Neoplasias Colorretais/patologia; Feminino; Humanos; Masculino; Camundongos; Camundongos Nus; Cadeias Pesadas de Miosina/genética; Células Tumorais Cultivadas

Palavras-chave

AMPK/mTOR pathway; CSCs markers; Cell survival; Colorectal cancer; NMIIA

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Cadeias Pesadas de Miosina / Proteínas Quinases Ativadas por AMP / Serina-Treonina Quinases TOR Tipo de estudo: Prognostic_studies Limite: Aged / Animals / Female / Humans / Male Idioma: En Revista: Exp Cell Res Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos

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