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An enolase inhibitor for the targeted treatment of ENO1-deleted cancers.
Lin, Yu-Hsi; Satani, Nikunj; Hammoudi, Naima; Yan, Victoria C; Barekatain, Yasaman; Khadka, Sunada; Ackroyd, Jeffrey J; Georgiou, Dimitra K; Pham, Cong-Dat; Arthur, Kenisha; Maxwell, David; Peng, Zhenghong; Leonard, Paul G; Czako, Barbara; Pisaneschi, Federica; Mandal, Pijus; Sun, Yuting; Zielinski, Rafal; Pando, Susana Castro; Wang, Xiaobo; Tran, Theresa; Xu, Quanyu; Wu, Qi; Jiang, Yongying; Kang, Zhijun; Asara, John M; Priebe, Waldemar; Bornmann, William; Marszalek, Joseph R; DePinho, Ronald A; Muller, Florian L.
Afiliação
  • Lin YH; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Satani N; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Hammoudi N; Institute of Stroke and Cerebrovascular Disease, University of Texas Health Science Center at Houston, Houston, TX, USA.
  • Yan VC; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Barekatain Y; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Khadka S; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Ackroyd JJ; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Georgiou DK; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pham CD; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Arthur K; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Maxwell D; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Peng Z; Institutional Analytics & Informatics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Leonard PG; Cardtronics, Inc, Houston, TX, USA.
  • Czako B; Core for Biomolecular Structure and Function, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pisaneschi F; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Mandal P; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Sun Y; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Zielinski R; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Pando SC; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wang X; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Tran T; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Xu Q; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Wu Q; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Jiang Y; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Kang Z; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Asara JM; Pharmaceutical Science Facility, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Priebe W; Institute for Applied Cancer Sciences, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • Bornmann W; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
  • Marszalek JR; Department of Experimental Therapeutics, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  • DePinho RA; Director of Drug Discovery and Development, Advanced Organic Synthesis LLC, Houston, Texas, USA.
  • Muller FL; Center for Co-Clinical Trials, University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nat Metab ; 2(12): 1413-1426, 2020 12.
Article em En | MEDLINE | ID: mdl-33230295
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfopiruvato Hidratase / Biomarcadores Tumorais / Proteínas Supressoras de Tumor / Proteínas de Ligação a DNA / Inibidores Enzimáticos / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfopiruvato Hidratase / Biomarcadores Tumorais / Proteínas Supressoras de Tumor / Proteínas de Ligação a DNA / Inibidores Enzimáticos / Neoplasias / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Metab Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha