2-Azidoacrylamides as compact platforms for efficient modular synthesis.

Takemura, Hinano; Goto, Sayuri; Hosoya, Takamitsu; Yoshida, Suguru

Takemura, Hinano; Goto, Sayuri; Hosoya, Takamitsu; Yoshida, Suguru.

Afiliação

Takemura H; Laboratory of Chemical Bioscience, Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan. s-yoshida.cb@tmd.ac.jp.

Chem Commun (Camb) ; 56(99): 15541-15544, 2020 Dec 25.

Article em En | MEDLINE | ID: mdl-33241832

ABSTRACT

ABSTRACT

Efficient methods to assemble modules with compact platform molecules by triazole formations and Michael reactions are disclosed. The good electrophilicity of 2-triazolylacrylamides realized Michael additions using various nucleophiles. An iterative synthesis of a tetrakis(triazole) was accomplished by orthogonal triazole formations and Michael reactions.

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Japão

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