Serology- and PCR-based cumulative incidence of SARS-CoV-2 infection in adults in a successfully contained early hotspot (CoMoLo study), Germany, May to June 2020.
Euro Surveill
; 25(47)2020 11.
Article
em En
| MEDLINE
| ID: mdl-33243353
ABSTRACT
Three months after a coronavirus disease (COVID-19) outbreak in Kupferzell, Germany, a population-based study (n = 2,203) found no RT-PCR-positives. IgG-ELISA seropositivity with positive virus neutralisation tests was 7.7% (95% confidence interval (CI) 6.5-9.1) and 4.3% with negative neutralisation tests. We estimate 12.0% (95% CI 10.4-14.0%) infected adults (24.5% asymptomatic), six times more than notified. Full hotspot containment confirms the effectiveness of prompt protection measures. However, 88% naïve adults are still at high COVID-19 risk.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia Viral
/
Reação em Cadeia da Polimerase
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Infecções por Coronavirus
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Coronavirus
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Teste de Ácido Nucleico para COVID-19
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Teste Sorológico para COVID-19
Tipo de estudo:
Diagnostic_studies
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Incidence_studies
/
Prognostic_studies
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Risk_factors_studies
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Screening_studies
Limite:
Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
Euro Surveill
Assunto da revista:
DOENCAS TRANSMISSIVEIS
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
Alemanha
