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Design, Synthesis, and Molecular Docking of Paracyclophanyl-Thiazole Hybrids as Novel CDK1 Inhibitors and Apoptosis Inducing Anti-Melanoma Agents.
Aly, Ashraf A; Bräse, Stefan; Hassan, Alaa A; Mohamed, Nasr K; El-Haleem, Lamiaa E Abd; Nieger, Martin; Morsy, Nesrin M; Alshammari, Mohammed B; Ibrahim, Mahmoud A A; Abdelhafez, Elshimaa M N.
Afiliação
  • Aly AA; Department of Chemistry, Faculty of Science, Minia University, El Minia 61519, Egypt.
  • Bräse S; Institute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
  • Hassan AA; Institute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, D-76344 Eggenstein-Leopoldshafen, Germany.
  • Mohamed NK; Department of Chemistry, Faculty of Science, Minia University, El Minia 61519, Egypt.
  • El-Haleem LEA; Department of Chemistry, Faculty of Science, Minia University, El Minia 61519, Egypt.
  • Nieger M; Institute of Organic Chemistry, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
  • Morsy NM; Institute of Biological and Chemical Systems-Functional Molecular Systems (IBCS-FMS), Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, D-76344 Eggenstein-Leopoldshafen, Germany.
  • Alshammari MB; Department of Chemistry, University of Helsinki, P.O. Box 55 (A. I. Virtasen aukio I), 00014 Helsinki, Finland.
  • Ibrahim MAA; National Research Centre, Organometallic and Organometalloid Chemistry Department, Dokki, Cairo 12622, Egypt.
  • Abdelhafez EMN; College of Sciences and Humanities, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Molecules ; 25(23)2020 Nov 27.
Article em En | MEDLINE | ID: mdl-33260954
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Desenho de Fármacos / Proteína Quinase CDC2 / Apoptose / Inibidores Enzimáticos / Melanoma / Naftóis / Antineoplásicos Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Egito País de publicação: Suíça
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiazóis / Desenho de Fármacos / Proteína Quinase CDC2 / Apoptose / Inibidores Enzimáticos / Melanoma / Naftóis / Antineoplásicos Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Egito País de publicação: Suíça