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Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.
de Boer, Jan Freark; de Vries, Hilde D; Palmiotti, Anna; Li, Rumei; Doestzada, Marwah; Hoogerland, Joanne A; Fu, Jingyuan; La Rose, Anouk M; Westerterp, Marit; Mulder, Niels L; Hovingh, Milaine V; Koehorst, Martijn; Kloosterhuis, Niels J; Wolters, Justina C; Bloks, Vincent W; Haas, Joel T; Dombrowicz, David; Staels, Bart; van de Sluis, Bart; Kuipers, Folkert.
Afiliação
  • de Boer JF; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address: j.f.de.boer@umcg.nl.
  • de Vries HD; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; University of Groningen, Campus Fryslân, Leeuwarden, the Netherlands.
  • Palmiotti A; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Li R; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Doestzada M; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands; Department of Genetics University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Hoogerland JA; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1011-EGID, F-59000 Lille, France.
  • Fu J; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands; Department of Genetics University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • La Rose AM; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Westerterp M; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Mulder NL; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Hovingh MV; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Koehorst M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Kloosterhuis NJ; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Wolters JC; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Bloks VW; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands.
  • Haas JT; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1011-EGID, F-59000 Lille, France.
  • Dombrowicz D; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1011-EGID, F-59000 Lille, France.
  • Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur Lille, U1011-EGID, F-59000 Lille, France.
  • van de Sluis B; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands; iPSC/CRISPR Center Groningen, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
  • Kuipers F; Department of Pediatrics, University of Groningen, University Medical Center Groningen, the Netherlands; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Cell Mol Gastroenterol Hepatol ; 11(4): 1045-1069, 2021.
Article em En | MEDLINE | ID: mdl-33309945

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Doenças Biliares / Fibrose / Ácidos e Sais Biliares / Colangite / Ácidos Cólicos / Sistema Enzimático do Citocromo P-450 Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Cell Mol Gastroenterol Hepatol Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácido Ursodesoxicólico / Doenças Biliares / Fibrose / Ácidos e Sais Biliares / Colangite / Ácidos Cólicos / Sistema Enzimático do Citocromo P-450 Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Cell Mol Gastroenterol Hepatol Ano de publicação: 2021 Tipo de documento: Article País de publicação: Estados Unidos