Circadian effects on stroke outcome - Did we not wake up in time for neuroprotection?
J Cereb Blood Flow Metab
; 41(3): 684-686, 2021 03.
Article
em En
| MEDLINE
| ID: mdl-33337257
ABSTRACT
The occurrence of stroke in humans peaks in the morning. A recent study revealed that time of day mitigates the therapeutic impact of neuroprotective paradigms. These findings might not only explain the previous failure of translation of neuroprotective therapies but inspire new paradigms in stroke chronopathophysiology research. Taking chronotype into account may complement the many factors that influence efficacy of experimental therapies in stroke.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acidente Vascular Cerebral
/
Relógios Circadianos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
J Cereb Blood Flow Metab
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Reino Unido