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Effects of acid and lactone forms of statins on S-warfarin 7-hydroxylation catalyzed by human liver microsomes and recombinant CYP2C9 variants (CYP2C9.1 and CYP2C9.3).
Shiozawa, Ayaka; Yamaori, Satoshi; Kamijo, Shinobu; Ohmori, Shigeru.
Afiliação
  • Shiozawa A; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
  • Yamaori S; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan. Electronic address: syamaori@shinshu-u.ac.jp.
  • Kamijo S; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
  • Ohmori S; Department of Pharmacy, Shinshu University Hospital, 3-1-1 Asahi, Matsumoto, 390-8621, Japan; Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University, 3-1-1 Asahi, Matsumoto, 390-8621, Japan.
Drug Metab Pharmacokinet ; 36: 100364, 2021 Feb.
Article em En | MEDLINE | ID: mdl-33341662
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Varfarina / Microssomos Hepáticos / Inibidores de Hidroximetilglutaril-CoA Redutases / Citocromo P-450 CYP2C9 / Variantes Farmacogenômicos Limite: Female / Humans / Male Idioma: En Revista: Drug Metab Pharmacokinet Assunto da revista: FARMACOLOGIA / METABOLISMO Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Varfarina / Microssomos Hepáticos / Inibidores de Hidroximetilglutaril-CoA Redutases / Citocromo P-450 CYP2C9 / Variantes Farmacogenômicos Limite: Female / Humans / Male Idioma: En Revista: Drug Metab Pharmacokinet Assunto da revista: FARMACOLOGIA / METABOLISMO Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido