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Heritable Human Genome Editing: The Public Engagement Imperative.
Adashi, Eli Y; Burgess, Michael M; Burall, Simon; Cohen, I Glenn; Fleck, Leonard M; Harris, John; Holm, Soren; Lafont, Cristina; Moreno, Jonathan D; Neblo, Michael A; Niemeyer, Simon J; Rowe, Eugene J; Scheufele, Dietram A; Tetsa, Paul F; Vayena, Effy; Watermeyer, Richard P; Fung, Archon.
Afiliação
  • Adashi EY; Department of Medical Science, Brown University, Providence, Rhode Island, USA.
  • Burgess MM; Department of Medical Genetics, University of British Columbia, Vancouver, Canada.
  • Burall S; Involve, London, United Kingdom.
  • Cohen IG; Harvard Law School, Harvard University, Cambridge, Massachusetts, USA.
  • Fleck LM; Department of Philosophy, Michigan State University, East Lansing, Michigan, USA.
  • Harris J; Department of Bioethics, King's College London, London, United Kingdom.
  • Holm S; Department of Bioethics, Manchester University, Manchester, United Kingdom.
  • Lafont C; Department of Philosophy, Northwestern University, Evanston, Illinois, USA.
  • Moreno JD; Departments of Medical Ethics and Health Policy, History and Sociology of Science, and Philosophy, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Neblo MA; Department of Political Science, Ohio State University, Columbus, Ohio, USA.
  • Niemeyer SJ; Centre for Deliberative Democracy and Global Governance, University of Canberra, Canberra, Australia.
  • Rowe EJ; Gene Rowe Evaluations, Norwich, United Kingdom.
  • Scheufele DA; Department of Life Sciences Communication, University of Wisconsin, Madison, Wisconsin, USA.
  • Tetsa PF; Department of Political Science, Brown University, Providence, Rhode Island, USA.
  • Vayena E; Department of Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
  • Watermeyer RP; School of Education, University of Bristol, Bristol, United Kingdom.
  • Fung A; Kennedy School, Harvard University, Cambridge, Massachusetts, USA.
CRISPR J ; 3(6): 434-439, 2020 12.
Article em En | MEDLINE | ID: mdl-33346718
ABSTRACT
In the view of many, heritable human genome editing (HHGE) harbors the remedial potential of ridding the world of deadly genetic diseases. A Hippocratic obligation, if there ever was one, HHGE is widely viewed as a life-sustaining proposition. The national go/no-go decision regarding the implementation of HHGE, however, must not, in the collective view of the authors, proceed absent thorough public engagement. A comparable call for an "extensive societal dialogue" was recently issued by the International Commission on the Clinical Use of Human Germline Genome Editing. In this communication, the authors lay out the foundational principles undergirding the formation, modification, and evaluation of public opinion. It is against this backdrop that the societal decision to warrant or enjoin the clinical conduct of HHGE will doubtlessly transpire.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edição de Genes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: CRISPR J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Edição de Genes Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: CRISPR J Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos