Inhibitory effects of baicalein against herpes simplex virus type 1.
Acta Pharm Sin B
; 10(12): 2323-2338, 2020 Dec.
Article
em En
| MEDLINE
| ID: mdl-33354504
Anti-HSV-1; Baicalein; CC50, 50% cytotoxic concentration; DCFH-DA, 2',7'-dichlorofluorescin diacetate; EC50, 50% effective concentration; GB, glycoprotein B; HSV-1 infection; HSV-1, herpes simplex virus types 1; ICP, infected cell polypeptide; IKK-ß phosphorylation; IKK-ß, IκB kinase beta; IL-1ß, interleukin 1 beta; IL-6, interleukin 6; IκB-α, inhibitor of NF-κB alpha; LPS, lipopolysaccharides; MOI, multiplicity of infection; NAC, N-acetyl-l-cysteine; NF-κB activation; NF-κB, nuclear factor kappa-B; PFU, plaque-forming units; PGA1, prostaglandin A1; ROS, reactive oxygen species; SI, selectivity index; TG, trigeminal ganglia; TNF-α, tumor necrosis factor alpha; Viral inactivation; dpi, days post-infection; p-IKK-ß, phosphorylated-IKK beta; p-IκB-α, phosphorylated-IκB alpha
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Acta Pharm Sin B
Ano de publicação:
2020
Tipo de documento:
Article
País de afiliação:
China
País de publicação:
Holanda