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The nucleotide prodrug CERC-913 improves mtDNA content in primary hepatocytes from DGUOK-deficient rats.
Vanden Avond, Mark A; Meng, Hui; Beatka, Margaret J; Helbling, Daniel C; Prom, Mariah J; Sutton, Jessica L; Slick, Rebecca A; Dimmock, David P; Pertusati, Fabrizio; Serpi, Michaela; Pileggi, Elisa; Crutcher, Patrick; Thomas, Stephen; Lawlor, Michael W.
Afiliação
  • Vanden Avond MA; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Meng H; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Beatka MJ; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Helbling DC; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Prom MJ; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Sutton JL; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Slick RA; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
  • Dimmock DP; Rady Children's Institute for Genomic Medicine, Rady Children's Hospital, San Diego, California, USA.
  • Pertusati F; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.
  • Serpi M; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.
  • Pileggi E; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK.
  • Crutcher P; Discovery R&D, Cerecor Inc., Rockville, Maryland, USA.
  • Thomas S; Discovery R&D, Cerecor Inc., Rockville, Maryland, USA.
  • Lawlor MW; Department of Pathology and Laboratory Medicine and Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
J Inherit Metab Dis ; 44(2): 492-501, 2021 03.
Article em En | MEDLINE | ID: mdl-33368311
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Fosfotransferases (Aceptor do Grupo Álcool) / Mitocôndrias / Nucleotídeos Limite: Animals / Female / Humans / Male Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Mitocondrial / Fosfotransferases (Aceptor do Grupo Álcool) / Mitocôndrias / Nucleotídeos Limite: Animals / Female / Humans / Male Idioma: En Revista: J Inherit Metab Dis Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos