Preliminary evidence on abatacept safety and efficacy in refractory juvenile localized scleroderma.

Li, Suzanne C; Torok, Kathryn S; Ishaq, Sarah S; Buckley, Mary; Edelheit, Barbara; Ede, Kaleo C; Liu, Christopher; Rabinovich, C Egla

Li, Suzanne C; Torok, Kathryn S; Ishaq, Sarah S; Buckley, Mary; Edelheit, Barbara; Ede, Kaleo C; Liu, Christopher; Rabinovich, C Egla.

Afiliação

Li SC; Department of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, NJ, USA.
Torok KS; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ishaq SS; Department of Biochemistry, Montclair State University, Montclair, NJ, USA.
Buckley M; Department of Pediatrics, Duke Children's Hospital and Health Center, Duke University School of Medicine, Durham, NC, USA.
Edelheit B; Department of Pediatrics, Connecticut Children's Medical Center, Hartford, CT, USA.
Ede KC; Department of Pediatrics, Phoenix Children's Hospital, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
Liu C; Department of Biochemistry, Montclair State University, Montclair, NJ, USA.
Rabinovich CE; Department of Pediatrics, Duke Children's Hospital and Health Center, Duke University School of Medicine, Durham, NC, USA.

Rheumatology (Oxford) ; 60(8): 3817-3825, 2021 08 02.

Article em En | MEDLINE | ID: mdl-33369667

Assuntos

Abatacepte/uso terapêutico; Antirreumáticos/uso terapêutico; Esclerodermia Localizada/tratamento farmacológico; Escleroderma Sistêmico/tratamento farmacológico; Adolescente; Criança; Estudos de Coortes; Feminino; Humanos; Masculino; Metotrexato/uso terapêutico; Ácido Micofenólico/uso terapêutico; Estudos Retrospectivos; Falha de Tratamento; Resultado do Tratamento

Palavras-chave

Localized scleroderma; biologic treatment; methotrexate; morphea; musculoskeletal activity; pediatric rheumatology; refractory; treatment failure

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esclerodermia Localizada / Escleroderma Sistêmico / Antirreumáticos / Abatacepte Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Risk_factors_studies Limite: Adolescent / Child / Female / Humans / Male Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido

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