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Identifying the Dominant Contribution of Human Cytochrome P450 2J2 to the Metabolism of Rivaroxaban, an Oral Anticoagulant.
Zhao, Tingting; Chen, Yanwei; Wang, Dalong; Wang, Liyan; Dong, Peipei; Zhao, Shan; Wang, Changyuan; Meng, Qiang; Sun, Huijun; Liu, Kexin; Wu, Jingjing.
Afiliação
  • Zhao T; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 9 West Section, Lvshun South Road, Lvshunkou District, Dalian, 116044, China.
  • Chen Y; Department of Pharmacy, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
  • Wang D; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 9 West Section, Lvshun South Road, Lvshunkou District, Dalian, 116044, China.
  • Wang L; Department of Pharmacy, The First Affiliated Hospital of Dalian Medical University, Dalian, 116011, China.
  • Dong P; College of Integrative Medicine, Dalian Medical University, Dalian, 116044, China.
  • Zhao S; Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116023, China.
  • Wang C; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 9 West Section, Lvshun South Road, Lvshunkou District, Dalian, 116044, China.
  • Meng Q; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning Dalian Medical University, Dalian, Liaoning, China.
  • Sun H; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 9 West Section, Lvshun South Road, Lvshunkou District, Dalian, 116044, China.
  • Liu K; Provincial Key Laboratory for Pharmacokinetics and Transport, Liaoning Dalian Medical University, Dalian, Liaoning, China.
  • Wu J; Department of Clinical Pharmacology, College of Pharmacy, Dalian Medical University, 9 West Section, Lvshun South Road, Lvshunkou District, Dalian, 116044, China.
Cardiovasc Drugs Ther ; 36(1): 121-129, 2022 02.
Article em En | MEDLINE | ID: mdl-33411110
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microssomos Hepáticos / Inibidores do Fator Xa / Rivaroxabana / Citocromo P-450 CYP2J2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cardiovasc Drugs Ther Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Microssomos Hepáticos / Inibidores do Fator Xa / Rivaroxabana / Citocromo P-450 CYP2J2 Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Cardiovasc Drugs Ther Assunto da revista: ANGIOLOGIA / CARDIOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos