Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-&#954;B signal pathway.

Qi, Min-You; He, Ying-Hao; Cheng, Yin; Fang, Qing; Ma, Ru-Yu; Zhou, Shao-Jie; Hao, Jia-Qi

Icariin ameliorates streptozocin-induced diabetic nephropathy through suppressing the TLR4/NF-κB signal pathway.

Qi, Min-You; He, Ying-Hao; Cheng, Yin; Fang, Qing; Ma, Ru-Yu; Zhou, Shao-Jie; Hao, Jia-Qi.

Afiliação

Qi MY; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
He YH; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
Cheng Y; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
Fang Q; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
Ma RY; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
Zhou SJ; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.
Hao JQ; Institution of Pharmacology, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, 310014, China. qiminyou@163.com.

Food Funct ; 12(3): 1241-1251, 2021 Feb 15.

Article em En | MEDLINE | ID: mdl-33433547

Assuntos

Diabetes Mellitus Experimental/complicações; Nefropatias Diabéticas/prevenção & controle; Flavonoides/farmacologia; NF-kappa B/metabolismo; Receptor 4 Toll-Like/metabolismo; Animais; Flavonoides/química; Regulação da Expressão Gênica/efeitos dos fármacos; Inflamação/tratamento farmacológico; Inflamação/etiologia; Rim/efeitos dos fármacos; Rim/patologia; Masculino; Camundongos; Camundongos Endogâmicos ICR; NF-kappa B/genética; Transdução de Sinais/efeitos dos fármacos; Receptor 4 Toll-Like/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Flavonoides / NF-kappa B / Diabetes Mellitus Experimental / Nefropatias Diabéticas / Receptor 4 Toll-Like Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Revista: Food Funct Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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