Fecal Microbiota Transplantation for Recurrent Clostridioides difficile Infection Enhances Adaptive Immunity to C difficile Toxin B.

Cook, Laura; Rees, William D; Wong, May Q; Peters, Hannah; Levings, Megan K; Steiner, Theodore S

Cook, Laura; Rees, William D; Wong, May Q; Peters, Hannah; Levings, Megan K; Steiner, Theodore S.

Afiliação

Cook L; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Rees WD; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Wong MQ; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
Peters H; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Levings MK; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada; Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada; School of Biomedical Engineering, University of British Columbia, Vancouver, British Columbia, C
Steiner TS; Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address: tsteiner@mail.ubc.ca.

Gastroenterology ; 160(6): 2155-2158.e4, 2021 05.

Article em En | MEDLINE | ID: mdl-33444574

Assuntos

Imunidade Adaptativa; Proteínas de Bactérias/imunologia; Toxinas Bacterianas/imunologia; Clostridioides difficile; Enterocolite Pseudomembranosa/terapia; Transplante de Microbiota Fecal; Células Th17; Adolescente; Adulto; Idoso; Idoso de 80 Anos ou mais; Enterotoxinas/imunologia; Feminino; Humanos; Imunoglobulina A/sangue; Imunoglobulina G/sangue; Interleucina-17/metabolismo; Interleucinas/metabolismo; Masculino; Pessoa de Meia-Idade; Receptores de Antígenos de Linfócitos T/metabolismo; Recidiva; Células Th17/metabolismo; Células Th2; Adulto Jovem; Interleucina 22

Palavras-chave

Antigen-specific; C difficile; CD4 T cell; Fecal Microbiota Transplant; T cell receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Toxinas Bacterianas / Enterocolite Pseudomembranosa / Clostridioides difficile / Imunidade Adaptativa / Células Th17 / Transplante de Microbiota Fecal Limite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Gastroenterology Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Canadá

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