Severe Relapses of Neuromyelitis Optica Spectrum Disorder During Treatment With Dimethyl Fumarate.
Clin Neuropharmacol
; 44(1): 21-22, 2021.
Article
em En
| MEDLINE
| ID: mdl-33449476
ABSTRACT
ABSTRACT Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system, characterized by a specific antibody that selectively binds aquaporin-4 channel.This is a report of an NMOSD case, with severe attacks of optic neuritis and myelitis after initiate of dimethyl fumarate (DMF).We suggested that DMF could deteriorate the neuromyelitis optica (NMO) disease course, which results in serious morbidity and mortality in patients. Thus, initiation of DMF should be avoided before ruling out NMOSD in patients experiencing demyelinating attacks, especially in the case of recurrent optic neuritis or myelopathy and concurrency of other rheumatologic diseases.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Índice de Gravidade de Doença
/
Neuromielite Óptica
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Fumarato de Dimetilo
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Imunossupressores
Limite:
Female
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Humans
/
Middle aged
Idioma:
En
Revista:
Clin Neuropharmacol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Irã