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Design and Evaluation of Peptide Dual-Agonists of GLP-1 and NPY2 Receptors for Glucoregulation and Weight Loss with Mitigated Nausea and Emesis.
Milliken, Brandon T; Elfers, Clinton; Chepurny, Oleg G; Chichura, Kylie S; Sweet, Ian R; Borner, Tito; Hayes, Matthew R; De Jonghe, Bart C; Holz, George G; Roth, Christian L; Doyle, Robert P.
Afiliação
  • Milliken BT; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
  • Elfers C; Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington 98105, United States.
  • Chepurny OG; Department of Medicine, State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Chichura KS; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
  • Sweet IR; Diabetes Research Institute, University of Washington, Seattle, Washington 98105, United States.
  • Borner T; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • Hayes MR; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • De Jonghe BC; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
  • Holz GG; Department of Medicine, State University of New York, Upstate Medical University, Syracuse, New York 13210, United States.
  • Roth CL; Department of Pediatrics, Seattle Children's Hospital, University of Washington, Seattle, Washington 98105, United States.
  • Doyle RP; Department of Chemistry, Syracuse University, 111 College Place, Syracuse, New York 13244, United States.
J Med Chem ; 64(2): 1127-1138, 2021 01 28.
Article em En | MEDLINE | ID: mdl-33449689
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vômito / Redução de Peso / Receptores de Neuropeptídeo Y / Receptor do Peptídeo Semelhante ao Glucagon 1 / Glucose / Náusea Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vômito / Redução de Peso / Receptores de Neuropeptídeo Y / Receptor do Peptídeo Semelhante ao Glucagon 1 / Glucose / Náusea Limite: Animals / Humans / Male Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos