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Avapritinib in unresectable or metastatic PDGFRA D842V-mutant gastrointestinal stromal tumours: Long-term efficacy and safety data from the NAVIGATOR phase I trial.
Jones, Robin L; Serrano, César; von Mehren, Margaret; George, Suzanne; Heinrich, Michael C; Kang, Yoon-Koo; Schöffski, Patrick; Cassier, Philippe A; Mir, Olivier; Chawla, Sant P; Eskens, Ferry A L M; Rutkowski, Piotr; Tap, William D; Zhou, Teresa; Roche, Maria; Bauer, Sebastian.
Afiliação
  • Jones RL; Royal Marsden Hospital and Institute of Cancer Research, London, UK. Electronic address: robin.jones@rmh.nhs.uk.
  • Serrano C; Vall d' Hebron Institute of Oncology, Barcelona, Spain.
  • von Mehren M; Fox Chase Cancer Center, Philadelphia, PA, USA.
  • George S; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Heinrich MC; Portland VA Health Care System and OHSU Knight Cancer Institute, Portland, OR, USA.
  • Kang YK; Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea.
  • Schöffski P; University Hospitals Leuven, Leuven Cancer Institute, Leuven, Belgium.
  • Cassier PA; Centre Léon Bérard, Lyon, France.
  • Mir O; Institut Gustave Roussy, Villejuif, France.
  • Chawla SP; Sarcoma Oncology Center, Santa Monica, CA, USA.
  • Eskens FALM; Erasmus MC Cancer Institute, Rotterdam, the Netherlands.
  • Rutkowski P; Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Tap WD; Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.
  • Zhou T; Blueprint Medicines Corporation, Cambridge, MA, USA.
  • Roche M; Blueprint Medicines Corporation, Cambridge, MA, USA.
  • Bauer S; Department of Medical Oncology, University Hospital Essen, Sarcoma Center, University of Duisburg-Essen, Essen, Germany.
Eur J Cancer ; 145: 132-142, 2021 03.
Article em En | MEDLINE | ID: mdl-33465704
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirróis / Triazinas / Receptor alfa de Fator de Crescimento Derivado de Plaquetas / Tumores do Estroma Gastrointestinal / Inibidores de Proteínas Quinases / Neoplasias Gastrointestinais / Mutação / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirazóis / Pirróis / Triazinas / Receptor alfa de Fator de Crescimento Derivado de Plaquetas / Tumores do Estroma Gastrointestinal / Inibidores de Proteínas Quinases / Neoplasias Gastrointestinais / Mutação / Antineoplásicos Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Eur J Cancer Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido