Blood-brain barrier integrity is the primary target of alcohol abuse.

Wei, Jiangping; Dai, Yuan; Wen, Wen; Li, Jin; Ye, Lingyu Linda; Xu, Shijun; Duan, Dayue Darrel

Wei, Jiangping; Dai, Yuan; Wen, Wen; Li, Jin; Ye, Lingyu Linda; Xu, Shijun; Duan, Dayue Darrel.

Afiliação

Wei J; Institute of Material Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China.
Dai Y; Institute of Material Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China; School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR
Wen W; Institute of Material Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China.
Li J; Institute of Material Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China; School of Health Preservation and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR
Ye LL; Center for Phenomics of Traditional Chinese Medicine and the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China.
Xu S; Institute of Material Medica Integration and Transformation for Brain Disorders, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, 611137, PR China. Electronic address: xus
Duan DD; Center for Phenomics of Traditional Chinese Medicine and the Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, 646000, China. Electronic address: dduan@swmu.edu.cn.

Chem Biol Interact ; 337: 109400, 2021 Mar 01.

Article em En | MEDLINE | ID: mdl-33516661

Assuntos

Barreira Hematoencefálica/efeitos dos fármacos; Etanol/toxicidade; Alcoolismo/metabolismo; Alcoolismo/patologia; Animais; Barreira Hematoencefálica/metabolismo; Modelos Animais de Doenças; Regulação para Baixo/efeitos dos fármacos; Galactose/toxicidade; Hipocampo/efeitos dos fármacos; Hipocampo/fisiologia; Lipopolissacarídeos/toxicidade; Proteína-1 Relacionada a Receptor de Lipoproteína de Baixa Densidade/metabolismo; Masculino; Aprendizagem em Labirinto/efeitos dos fármacos; Camundongos; Ocludina/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Permeabilidade/efeitos dos fármacos; Proteína da Zônula de Oclusão-1/metabolismo

Palavras-chave

Alcohol abuse; Blood-brain barrier integrity; Cognitive deficit; Lipopolysaccharide; d-galactose

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Etanol Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Chem Biol Interact Ano de publicação: 2021 Tipo de documento: Article País de publicação: Irlanda

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