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A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy in patients with advanced cancer.
Geenen, Jill J J; Dackus, Gwen M H E; Schouten, Philip C; Pluim, Dick; Marchetti, Serena; Sonke, Gabe S; Józwiak, Katarzyna; Huitema, Alwin D R; Beijnen, Jos H; Schellens, Jan H M; Linn, Sabine C.
Afiliação
  • Geenen JJJ; Department of Clinical Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Dackus GMHE; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Schouten PC; Department of Molecular Pathology, Antoni van Leeuwenhoek Hospital - Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Pluim D; Department of Pathology, Utrecht University Medical Center, Utrecht, The Netherlands.
  • Marchetti S; Department of Molecular Pathology, Antoni van Leeuwenhoek Hospital - Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Sonke GS; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Józwiak K; Division of Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Huitema ADR; Department of Medical Oncology, Antoni van Leeuwenhoek Hospital - Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Beijnen JH; Department of Medical Oncology, Antoni van Leeuwenhoek Hospital - Netherlands Cancer Institute, Amsterdam, The Netherlands.
  • Schellens JHM; Brandenburg Medical School Theodor Fontane, Institute of Biostatistics and Registry Research, Neuruppin, Germany.
  • Linn SC; Department of Clinical Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Int J Cancer ; 148(12): 3041-3050, 2021 06 15.
Article em En | MEDLINE | ID: mdl-33539540

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Protocolos de Quimioterapia Combinada Antineoplásica / Carboplatina / Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ftalazinas / Piperazinas / Protocolos de Quimioterapia Combinada Antineoplásica / Carboplatina / Neoplasias Tipo de estudo: Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Int J Cancer Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Holanda País de publicação: Estados Unidos