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Discovery of small molecule positive allosteric modulators of the secretin receptor.
Dengler, Daniela G; Harikumar, Kaleeckal G; Pollari, Sirkku; Sun, Qing; Brown, Brock T; Shinoki-Iwaya, Aki; Ardecky, Robert; Miller, Laurence J; Sergienko, Eduard A.
Afiliação
  • Dengler DG; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. Electronic address: ddengler@sbpdiscovery.org.
  • Harikumar KG; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ, USA.
  • Pollari S; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Sun Q; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Brown BT; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Shinoki-Iwaya A; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Ardecky R; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
  • Miller LJ; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Scottsdale, AZ, USA.
  • Sergienko EA; Conrad Prebys Center for Chemical Genomics, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA. Electronic address: esergien@sbpdiscovery.org.
Biochem Pharmacol ; 185: 114451, 2021 03.
Article em En | MEDLINE | ID: mdl-33545115
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Receptores dos Hormônios Gastrointestinais / Receptores Acoplados a Proteínas G / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Receptores dos Hormônios Gastrointestinais / Receptores Acoplados a Proteínas G / Descoberta de Drogas Limite: Animals / Humans Idioma: En Revista: Biochem Pharmacol Ano de publicação: 2021 Tipo de documento: Article