Effects of armodafinil nanocrystal nasal hydrogel on recovery of cognitive function in sleep-deprived rats.

Zhu, Siqing; Zhang, Shouguo; Pang, Lulu; Ou, Ge; Zhu, Lin; Ma, Jinqiu; Li, Ruiteng; Liu, Yijing; Wang, Lin; Wang, Lifeng; Du, Lina; Jin, Yiguang

Zhu, Siqing; Zhang, Shouguo; Pang, Lulu; Ou, Ge; Zhu, Lin; Ma, Jinqiu; Li, Ruiteng; Liu, Yijing; Wang, Lin; Wang, Lifeng; Du, Lina; Jin, Yiguang.

Afiliação

Zhu S; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; Anhui Medical University, Hefei 230032, China.
Zhang S; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Pang L; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Ou G; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; General Hospital of PLA, Beijing 100853, China.
Zhu L; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Ma J; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Li R; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Liu Y; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
Wang L; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China.
Wang L; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China. Electronic address: fangchangwlf@sina.com.
Du L; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; Anhui Medical University, Hefei 230032, China; School of Medicine, Shandong University of Traditional Chinese Medicine, Jinan 250355, China. Electronic address: dulina@188.com.
Jin Y; Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing 100850, China; Anhui Medical University, Hefei 230032, China. Electronic address: jinyg@sina.com.

Int J Pharm ; 597: 120343, 2021 Mar 15.

Article em En | MEDLINE | ID: mdl-33545288

Assuntos

Hidrogéis; Nanopartículas; Animais; Compostos Benzidrílicos; Cognição; Método Duplo-Cego; Humanos; Modafinila; Ratos; Sono

Palavras-chave

Armodafinil; Brain targeting; Intranasal delivery; Nanocrystals; Sleep deprivation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hidrogéis / Nanopartículas Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Int J Pharm Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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