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Mitochondrial uncoupler SHC517 reverses obesity in mice without affecting food intake.
Chen, Sing-Young; Beretta, Martina; Alexopoulos, Stephanie J; Shah, Divya P; Olzomer, Ellen M; Hargett, Stefan R; Childress, Elizabeth S; Salamoun, Joseph M; Aleksovska, Isabella; Roseblade, Ariane; Cranfield, Charles; Rawling, Tristan; Quinlan, Kate G R; Morris, Margaret J; Tucker, Simon P; Santos, Webster L; Hoehn, Kyle L.
Afiliação
  • Chen SY; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Beretta M; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Alexopoulos SJ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Shah DP; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Olzomer EM; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Hargett SR; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
  • Childress ES; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA 24061, USA.
  • Salamoun JM; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA 24061, USA.
  • Aleksovska I; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Roseblade A; School of Mathematical and Physical Sciences, University of Technology, Sydney, NSW 2007, Australia.
  • Cranfield C; School of Life Sciences, University of Technology, Sydney, NSW 2007, Australia.
  • Rawling T; School of Mathematical and Physical Sciences, University of Technology, Sydney, NSW 2007, Australia.
  • Quinlan KGR; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Morris MJ; School of Medical Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
  • Tucker SP; Continuum Biosciences Pty Ltd., Sydney, NSW, 2035, Australia.
  • Santos WL; Department of Chemistry and Virginia Tech Centre for Drug Discovery, Virginia Tech, Blacksburg, VA 24061, USA; Continuum Biosciences Pty Ltd., Sydney, NSW, 2035, Australia. Electronic address: santosw@vt.edu.
  • Hoehn KL; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia; Department of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.; Continuum Biosciences Pty Ltd., Sydney, NSW, 2035, Australia. Electronic address: k.hoehn@unsw.edu.au.
Metabolism ; 117: 154724, 2021 04.
Article em En | MEDLINE | ID: mdl-33548253

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ingestão de Alimentos / Bibliotecas de Moléculas Pequenas / Mitocôndrias / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Metabolism Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ingestão de Alimentos / Bibliotecas de Moléculas Pequenas / Mitocôndrias / Obesidade Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Metabolism Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Austrália País de publicação: Estados Unidos