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XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis.
Boons, Eline; Nogueira, Tatiane C; Dierckx, Tim; Menezes, Soraya Maria; Jacquemyn, Maarten; Tamir, Sharon; Landesman, Yosef; Farré, Lourdes; Bittencourt, Achiléa; Kataoka, Keisuke; Ogawa, Seishi; Snoeck, Robert; Andrei, Graciela; Van Weyenbergh, Johan; Daelemans, Dirk.
Afiliação
  • Boons E; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium.
  • Nogueira TC; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium.
  • Dierckx T; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000, Leuven, Belgium.
  • Menezes SM; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000, Leuven, Belgium.
  • Jacquemyn M; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium.
  • Tamir S; Karyopharm Therapeutics, Newton, MA, USA.
  • Landesman Y; Karyopharm Therapeutics, Newton, MA, USA.
  • Farré L; Instituto de Pesquisa Goncalo Moniz, Oswaldo Cruz Foundation (FIOCRUZ), Salvador, Bahia, Brazil.
  • Bittencourt A; HUPES, Federal University of Bahia (UFBA), Salvador-Bahia, Brazil.
  • Kataoka K; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Ogawa S; Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan.
  • Snoeck R; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium.
  • Andrei G; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium.
  • Van Weyenbergh J; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Clinical and Epidemiological Virology, Rega Institute, B-3000, Leuven, Belgium.
  • Daelemans D; KU Leuven Department of Microbiology, Immunology and Transplantation, Laboratory of Virology and Chemotherapy, Rega Institute, B-3000, Leuven, Belgium. dirk.daelemans@kuleuven.be.
Blood Cancer J ; 11(2): 27, 2021 02 01.
Article em En | MEDLINE | ID: mdl-33563902
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Leucemia-Linfoma de Células T do Adulto / Proteína Supressora de Tumor p53 / Apoptose / Receptores Citoplasmáticos e Nucleares / Carioferinas / Hidrazinas Limite: Humans Idioma: En Revista: Blood Cancer J Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Triazóis / Leucemia-Linfoma de Células T do Adulto / Proteína Supressora de Tumor p53 / Apoptose / Receptores Citoplasmáticos e Nucleares / Carioferinas / Hidrazinas Limite: Humans Idioma: En Revista: Blood Cancer J Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos