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The quinazoline derivative, 04NB-03, induces cell cycle arrest and apoptosis in hepatocellular carcinoma cells in a reactive oxygen species-dependent manner.
Wang, Rongze; Zhu, Yexuan; Chen, Jingyi; Wang, Yiliang; Song, Xiaowei; Wu, Yanting; Jin, Fujun; Wang, Yifei.
Afiliação
  • Wang R; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Zhu Y; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Chen J; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Wang Y; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Song X; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Wu Y; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China.
  • Jin F; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China; Integrated Chinese and Western Medicine Postdoctoral Research St
  • Wang Y; Guangzhou Jinan Biomedicine Research and Development Center, Key Laboratory of Bioengineering Medicine of Guangdong Province, Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China; Key Laboratory of Virology of Guangzhou, Jinan University, Guang
Chem Biol Interact ; 338: 109371, 2021 Apr 01.
Article em En | MEDLINE | ID: mdl-33582112

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Espécies Reativas de Oxigênio / Apoptose / Carcinoma Hepatocelular / Pontos de Checagem do Ciclo Celular / Neoplasias Hepáticas Limite: Animals / Female / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Irlanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Quinazolinas / Espécies Reativas de Oxigênio / Apoptose / Carcinoma Hepatocelular / Pontos de Checagem do Ciclo Celular / Neoplasias Hepáticas Limite: Animals / Female / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Irlanda