Inhibition of soluble epoxide hydrolase (sEH) protects hippocampal neurons and reduces cognitive decline in type 2 diabetic mice.

Wu, Jing; Fan, Zhen; Zhao, Yuxing; Chen, Qiunan; Xiao, Qian

Wu, Jing; Fan, Zhen; Zhao, Yuxing; Chen, Qiunan; Xiao, Qian.

Afiliação

Wu J; Department of Geriatrics, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Fan Z; Department of Geriatrics, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Zhao Y; Department of Geriatrics, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Chen Q; Department of Geriatrics, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiao Q; Department of Geriatrics, First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Eur J Neurosci ; 53(8): 2532-2540, 2021 04.

Article em En | MEDLINE | ID: mdl-33595911

Assuntos

Disfunção Cognitiva; Diabetes Mellitus Experimental; Diabetes Mellitus Tipo 2; Animais; Inibidores Enzimáticos; Epóxido Hidrolases/metabolismo; Hipocampo/metabolismo; Camundongos; Neurônios/metabolismo

Palavras-chave

Pyk2; ROS; diabetes; hippocampus; sEH inhibitor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Experimental / Diabetes Mellitus Tipo 2 / Disfunção Cognitiva Limite: Animals Idioma: En Revista: Eur J Neurosci Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: França

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