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BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia.
Herbaux, Charles; Kornauth, Christoph; Poulain, Stéphanie; Chong, Stephen J F; Collins, Mary C; Valentin, Rebecca; Hackett, Liam; Tournilhac, Olivier; Lemonnier, François; Dupuis, Jehan; Daniel, Adrien; Tomowiak, Cecile; Laribi, Kamel; Renaud, Loïc; Roos-Weil, Damien; Rossi, Cedric; Van Den Neste, Eric; Leyronnas, Cecile; Merabet, Fatiha; Malfuson, Jean Valère; Tiab, Mourad; Ysebaert, Loïc; Ng, Samuel; Morschhauser, Franck; Staber, Philipp B; Davids, Matthew S.
Afiliação
  • Herbaux C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Kornauth C; "CANcer Heterogeneity, Plasticity and Resistance to THERapies (CANTHER)," INSERM 1277, Centre National de la Recherche Scientifique (CNRS) 9020, Unité Mixte de Recherche en Santé (UMRS) 12, University of Lille, Lille, France.
  • Poulain S; Department of Blood Diseases, Centre Hospitalier Université (CHU) de Lille, Lille, France.
  • Chong SJF; Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria.
  • Collins MC; "CANcer Heterogeneity, Plasticity and Resistance to THERapies (CANTHER)," INSERM 1277, Centre National de la Recherche Scientifique (CNRS) 9020, Unité Mixte de Recherche en Santé (UMRS) 12, University of Lille, Lille, France.
  • Valentin R; Hematology Laboratory, Biology and Pathology Center, CHU de Lille, Lille, France.
  • Hackett L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Tournilhac O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Lemonnier F; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Dupuis J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
  • Daniel A; Clonal Heterogeneity and Leukemic Environment in Therapy Resistance of Chronic Leukemias (CHELTER), Department of Clinical Hematology and Cellular Therapy, CHU, EA7453, Université Clermont Auvergne, Clermont Ferrand, France.
  • Tomowiak C; Lymphoid Malignancies Unit, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.
  • Laribi K; Lymphoid Malignancies Unit, Henri Mondor University Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Créteil, France.
  • Renaud L; Department of Blood Diseases, Centre Hospitalier Université (CHU) de Lille, Lille, France.
  • Roos-Weil D; Hematology, Poitiers University Hospital, INSERM Clinical Investigation Center (CIC) 1402, Poitiers, France.
  • Rossi C; Department of Hematology, Centre Hospitalier Du Mans, Le Mans, France.
  • Van Den Neste E; Department of Blood Diseases, Centre Hospitalier Université (CHU) de Lille, Lille, France.
  • Leyronnas C; Service d'Hématologie Clinique, Hôpital Pitié-Salpêtrière, AP-HP, Sorbonne Université, Paris, France.
  • Merabet F; Department of Hematology, CHU Dijon, Dijon, France.
  • Malfuson JV; Department of Hematology, Saint-Luc University Hospital, Brussels, Belgium.
  • Tiab M; Institut Daniel Hollard, Grenoble, France.
  • Ysebaert L; Department of Hematology and Oncology, Hôpital André Mignot, Le Chesnay, France.
  • Ng S; Department of Hematology, Hôpital Percy, Clamart, France.
  • Morschhauser F; University Hospital, La Roche-sur-Yon, France; and.
  • Staber PB; Service d'Hématologie, Institut Universitaire du Cancer Toulouse-Oncopôle, Toulouse, France.
  • Davids MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.
Blood ; 137(25): 3495-3506, 2021 06 24.
Article em En | MEDLINE | ID: mdl-33598678
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Prolinfocítica de Células T / Protocolos de Quimioterapia Combinada Antineoplásica / Sistema de Sinalização das MAP Quinases / Proteínas de Neoplasias Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Prolinfocítica de Células T / Protocolos de Quimioterapia Combinada Antineoplásica / Sistema de Sinalização das MAP Quinases / Proteínas de Neoplasias Tipo de estudo: Clinical_trials Limite: Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Marrocos País de publicação: Estados Unidos