Harnessing A3G for efficient and selective C-to-T conversion at C-rich sequences.

Yu, Wenxia; Li, Jianan; Huang, Shisheng; Li, Xiangyang; Li, Ping; Li, Guanglei; Liang, Aibin; Chi, Tian; Huang, Xingxu

Yu, Wenxia; Li, Jianan; Huang, Shisheng; Li, Xiangyang; Li, Ping; Li, Guanglei; Liang, Aibin; Chi, Tian; Huang, Xingxu.

Afiliação

Yu W; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Li J; University of Chinese Academy of Sciences, Beijing, 100049, China.
Huang S; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Li X; University of Chinese Academy of Sciences, Beijing, 100049, China.
Li P; Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, 200031, China.
Li G; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Liang A; University of Chinese Academy of Sciences, Beijing, 100049, China.
Chi T; School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
Huang X; University of Chinese Academy of Sciences, Beijing, 100049, China.

BMC Biol ; 19(1): 34, 2021 02 18.

Article em En | MEDLINE | ID: mdl-33602235

Assuntos

Desaminase APOBEC-3G/genética; Sistemas CRISPR-Cas; Citidina Desaminase/metabolismo; Edição de Genes; RNA Guia de Cinetoplastídeos

Palavras-chave

Apobec 3G; Base editing; C-rich; Motif

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Guia de Cinetoplastídeos / Citidina Desaminase / Sistemas CRISPR-Cas / Desaminase APOBEC-3G / Edição de Genes Idioma: En Revista: BMC Biol Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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