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Sorafenib blocks the activation of the HIF-2α/VEGFA/EphA2 pathway, and inhibits the rapid growth of residual liver cancer following high-intensity focused ultrasound therapy in vivo.
Wu, Lun; Zhou, Jiao; Zhou, Wenbo; Huang, Xue-Fei; Chen, Qinhua; Wang, Wei; Zhai, Lulu; Li, Shengwei; Tang, Zhigang.
Afiliação
  • Wu L; Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Wuhan Province, PR China; Liver Surgery Institute of Experiment Center of Medicine, Department of Hepatobiliary Surgery, Affliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei 442001, PR China.
  • Zhou J; Department of Urology, Affliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei 442001, PR China.
  • Zhou W; Liver Surgery Institute of Experiment Center of Medicine, Department of Hepatobiliary Surgery, Affliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei 442001, PR China.
  • Huang XF; Liver Surgery Institute of Experiment Center of Medicine, Department of Hepatobiliary Surgery, Affliated Dongfeng Hospital, Hubei University of Medicine, Shiyan, Hubei 442001, PR China.
  • Chen Q; Shenzhen Baoan Authentic TCM Therapy Hospital, Shenzhen Guangdong, 518101, PR China.
  • Wang W; Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Wuhan Province, PR China.
  • Zhai L; Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Wuhan Province, PR China.
  • Li S; The Department of Hepatobiliary Surgery, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China.
  • Tang Z; Department of Pancreatic Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, Wuhan Province, PR China. Electronic address: tzg7031@163.com.
Pathol Res Pract ; 220: 153270, 2021 Apr.
Article em En | MEDLINE | ID: mdl-33640712

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Inibidores da Angiogênese / Receptor EphA2 / Fator A de Crescimento do Endotélio Vascular / Inibidores de Proteínas Quinases / Proliferação de Células / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Ablação por Ultrassom Focalizado de Alta Intensidade / Sorafenibe / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pathol Res Pract Ano de publicação: 2021 Tipo de documento: Article País de publicação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / Inibidores da Angiogênese / Receptor EphA2 / Fator A de Crescimento do Endotélio Vascular / Inibidores de Proteínas Quinases / Proliferação de Células / Fatores de Transcrição Hélice-Alça-Hélice Básicos / Ablação por Ultrassom Focalizado de Alta Intensidade / Sorafenibe / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Pathol Res Pract Ano de publicação: 2021 Tipo de documento: Article País de publicação: Alemanha