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Targeting a neoantigen derived from a common TP53 mutation.
Hsiue, Emily Han-Chung; Wright, Katharine M; Douglass, Jacqueline; Hwang, Michael S; Mog, Brian J; Pearlman, Alexander H; Paul, Suman; DiNapoli, Sarah R; Konig, Maximilian F; Wang, Qing; Schaefer, Annika; Miller, Michelle S; Skora, Andrew D; Azurmendi, P Aitana; Murphy, Michael B; Liu, Qiang; Watson, Evangeline; Li, Yana; Pardoll, Drew M; Bettegowda, Chetan; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Gabelli, Sandra B; Zhou, Shibin.
Afiliação
  • Hsiue EH; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Wright KM; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Douglass J; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Hwang MS; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Mog BJ; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Pearlman AH; Bloomberg~Kimmel Institute for Cancer Immunotherapy, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD 21287, USA.
  • Paul S; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • DiNapoli SR; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Konig MF; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Wang Q; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Schaefer A; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Miller MS; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Skora AD; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Azurmendi PA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Murphy MB; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Liu Q; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
  • Watson E; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Li Y; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Pardoll DM; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Bettegowda C; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Papadopoulos N; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
  • Kinzler KW; Lustgarten Pancreatic Cancer Research Laboratory, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Vogelstein B; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Gabelli SB; Ludwig Center, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
  • Zhou S; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA.
Science ; 371(6533)2021 03 05.
Article em En | MEDLINE | ID: mdl-33649166
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígeno HLA-A2 / Proteína Supressora de Tumor p53 / Anticorpos Biespecíficos / Anticorpos Antineoplásicos / Antígenos de Neoplasias / Neoplasias Limite: Animals / Female / Humans Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antígeno HLA-A2 / Proteína Supressora de Tumor p53 / Anticorpos Biespecíficos / Anticorpos Antineoplásicos / Antígenos de Neoplasias / Neoplasias Limite: Animals / Female / Humans Idioma: En Revista: Science Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos