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Inhibition of hypoxia inducible factor 1 by YC-1 attenuates tissue plasminogen activator induced hemorrhagic transformation by suppressing HMGB1/TLR4/NF-κB mediated neutrophil infiltration in thromboembolic stroke rats.
Kong, Linglei; Ma, Yinzhong; Wang, Zhiyuan; Liu, Nannan; Ma, Guodong; Liu, Chengdi; Shi, Ruili; Du, Guanhua.
Afiliação
  • Kong L; Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Ma Y; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China.
  • Wang Z; State Key Laboratory of Toxicology and Medical Countermeasures, Beijing Key Laboratory of Neuropsychopharmacology, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
  • Liu N; Guangdong Pharmaceutical University, Guangzhou 510006, China.
  • Ma G; Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Liu C; Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.
  • Shi R; Department of Physiology, Baotou Medical College, Baotou 014060, China. Electronic address: ruilishi@sina.com.
  • Du G; Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Centre for Pharmaceutical Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China. Electronic address: dugh@imm.ac.cn.
Int Immunopharmacol ; 94: 107507, 2021 May.
Article em En | MEDLINE | ID: mdl-33657523
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tromboembolia / Hemorragia Cerebral / Isquemia Encefálica / Ativador de Plasminogênio Tecidual / Acidente Vascular Cerebral / Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tromboembolia / Hemorragia Cerebral / Isquemia Encefálica / Ativador de Plasminogênio Tecidual / Acidente Vascular Cerebral / Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Int Immunopharmacol Assunto da revista: ALERGIA E IMUNOLOGIA / FARMACOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Holanda