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Functional convergence of a germline-encoded neutralizing antibody response in rhesus macaques immunized with HCV envelope glycoproteins.
Chen, Fang; Tzarum, Netanel; Lin, Xiaohe; Giang, Erick; Velázquez-Moctezuma, Rodrigo; Augestad, Elias H; Nagy, Kenna; He, Linling; Hernandez, Mayda; Fouch, Mallorie E; Grinyó, Ariadna; Chavez, Deborah; Doranz, Benjamin J; Prentoe, Jannick; Stanfield, Robyn L; Lanford, Robert; Bukh, Jens; Wilson, Ian A; Zhu, Jiang; Law, Mansun.
Afiliação
  • Chen F; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Tzarum N; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lin X; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Giang E; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Velázquez-Moctezuma R; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
  • Augestad EH; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
  • Nagy K; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • He L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Hernandez M; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Fouch ME; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Grinyó A; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Chavez D; Southwest National Primate Research Center at Texas Biomedical Research Institute, San Antonio, TX 788227, USA.
  • Doranz BJ; Integral Molecular, Inc., Philadelphia, PA 19104, USA.
  • Prentoe J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
  • Stanfield RL; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
  • Lanford R; Southwest National Primate Research Center at Texas Biomedical Research Institute, San Antonio, TX 788227, USA.
  • Bukh J; Copenhagen Hepatitis C Program (CO-HEP), Department of Infectious Diseases, Hvidovre Hospital, and Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.
  • Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: wilson@scripps.edu.
  • Zhu J; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: jiang@scripps.edu.
  • Law M; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: mlaw@scripps.edu.
Immunity ; 54(4): 781-796.e4, 2021 04 13.
Article em En | MEDLINE | ID: mdl-33675683
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Proteínas do Envelope Viral / Hepatite C / Hepacivirus / Anticorpos Neutralizantes / Células Germinativas / Macaca mulatta Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glicoproteínas / Proteínas do Envelope Viral / Hepatite C / Hepacivirus / Anticorpos Neutralizantes / Células Germinativas / Macaca mulatta Tipo de estudo: Observational_studies Limite: Animals / Humans Idioma: En Revista: Immunity Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos