Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity.

Hirayanagi, Kimitoshi; Ozaki, Hiroaki; Tsukagoshi, Setsuki; Furuta, Natsumi; Ikeda, Yoshio

Hirayanagi, Kimitoshi; Ozaki, Hiroaki; Tsukagoshi, Setsuki; Furuta, Natsumi; Ikeda, Yoshio.

Afiliação

Hirayanagi K; Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.
Ozaki H; Division of Pure and Applied Science, Faculty of Science and Technology, Gunma University, Maebashi, Gunma, 371-8510, Japan.
Tsukagoshi S; Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.
Furuta N; Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan.
Ikeda Y; Department of Neurology, Gunma University Graduate School of Medicine, Maebashi, Gunma, 371-8511, Japan. Electronic address: ikeday006@gunma-u.ac.jp.

Neurosci Res ; 171: 92-102, 2021 Oct.

Article em En | MEDLINE | ID: mdl-33705846

Assuntos

Esclerose Lateral Amiotrófica; Porfirinas; Ataxias Espinocerebelares; Esclerose Lateral Amiotrófica/genética; Humanos; Íntrons; Proteínas Nucleares/genética; Porfirinas/farmacologia; RNA; Ataxias Espinocerebelares/genética

Palavras-chave

G-quadruplex; Hemin chloride; Hexanucleotide GGCCTG repeat expansion; Porphyrin; RNA foci; Sodium copper chlorophyllin; Spinocerebellar ataxia type 36

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Porfirinas / Ataxias Espinocerebelares / Esclerose Lateral Amiotrófica Limite: Humans Idioma: En Revista: Neurosci Res Assunto da revista: NEUROLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Japão

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