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Mapping specificity, cleavage entropy, allosteric changes and substrates of blood proteases in a high-throughput screen.
Uliana, Federico; Vizovisek, Matej; Acquasaliente, Laura; Ciuffa, Rodolfo; Fossati, Andrea; Frommelt, Fabian; Goetze, Sandra; Wollscheid, Bernd; Gstaiger, Matthias; De Filippis, Vincenzo; Auf dem Keller, Ulrich; Aebersold, Ruedi.
Afiliação
  • Uliana F; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Vizovisek M; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Acquasaliente L; Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Protein Chemistry and Molecular Hematology, University of Padua, Padua, Italy.
  • Ciuffa R; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Fossati A; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Frommelt F; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Goetze S; Department of Health Sciences and Technology, Institute of Translational Medicine, ETH Zürich, Zürich, Switzerland.
  • Wollscheid B; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Gstaiger M; Department of Health Sciences and Technology, Institute of Translational Medicine, ETH Zürich, Zürich, Switzerland.
  • De Filippis V; Swiss Institute of Bioinformatics, Lausanne, Switzerland.
  • Auf dem Keller U; Department of Biology, Institute of Molecular Systems Biology, ETH Zürich, Zürich, Switzerland.
  • Aebersold R; Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Protein Chemistry and Molecular Hematology, University of Padua, Padua, Italy.
Nat Commun ; 12(1): 1693, 2021 03 16.
Article em En | MEDLINE | ID: mdl-33727531
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Entropia / Ensaios de Triagem em Larga Escala Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeo Hidrolases / Entropia / Ensaios de Triagem em Larga Escala Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Suíça País de publicação: Reino Unido