Combining segmental bulk- and single-cell RNA-sequencing to define the chondrocyte gene expression signature in the murine knee joint.

Sunkara, V; Heinz, G A; Heinrich, F F; Durek, P; Mobasheri, A; Mashreghi, M-F; Lang, A

Sunkara, V; Heinz, G A; Heinrich, F F; Durek, P; Mobasheri, A; Mashreghi, M-F; Lang, A.

Afiliação

Sunkara V; Explainable A.I. for Biology, Zuse Institute Berlin, Berlin, Germany; Department of Mathematics and Computer Science, Freie Universität Berlin, Germany. Electronic address: sunkara@mi.fu-berlin.de.
Heinz GA; German Rheumatism Research Centre (DRFZ) Berlin, A Leibniz Institute, Berlin, Germany.
Heinrich FF; German Rheumatism Research Centre (DRFZ) Berlin, A Leibniz Institute, Berlin, Germany.
Durek P; German Rheumatism Research Centre (DRFZ) Berlin, A Leibniz Institute, Berlin, Germany.
Mobasheri A; Research Unit of Medical Imaging, Physics and Technology, Faculty of Medicine, University of Oulu, Oulu, Finland; Department of Regenerative Medicine, State Research Institute, Centre for Innovative Medicine, Vilnius, Lithuania; University Medical Center Utrecht, Departments of Orthopedics, Rheumato
Mashreghi MF; German Rheumatism Research Centre (DRFZ) Berlin, A Leibniz Institute, Berlin, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Pediatrics, Division of Pulmonology, Immunology and Critical Care Medicine, Berl
Lang A; German Rheumatism Research Centre (DRFZ) Berlin, A Leibniz Institute, Berlin, Germany; Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Rheumatology and Clinical Immunology, Berlin, Germany. Electronic address: annem

Osteoarthritis Cartilage ; 29(6): 905-914, 2021 06.

Article em En | MEDLINE | ID: mdl-33762205

Assuntos

Cartilagem Articular/química; Condrócitos; RNA/análise; Análise de Sequência de RNA/métodos; Animais; Masculino; Camundongos; Camundongos Endogâmicos C57BL

Palavras-chave

Articular cartilage; Cellular phenotyping; Chondrocytes; Mouse models; RNA-seq; scRNA-seq

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA / Cartilagem Articular / Análise de Sequência de RNA / Condrócitos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Osteoarthritis Cartilage Assunto da revista: ORTOPEDIA / REUMATOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de publicação: Reino Unido

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