Assessing Ribosome Distribution Along Transcripts with Polarity Scores and Regression Slope Estimates.

Vorontsov, Ilya E; Egorov, Artyom A; Anisimova, Aleksandra S; Eliseeva, Irina A; Makeev, Vsevolod J; Gladyshev, Vadim N; Dmitriev, Sergey E; Kulakovskiy, Ivan V

Vorontsov, Ilya E; Egorov, Artyom A; Anisimova, Aleksandra S; Eliseeva, Irina A; Makeev, Vsevolod J; Gladyshev, Vadim N; Dmitriev, Sergey E; Kulakovskiy, Ivan V.

Afiliação

Vorontsov IE; Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
Egorov AA; Institute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
Anisimova AS; Phystech School of Biological and Medical Physics, Moscow Institute of Physics and Technology (State University), Dolgoprudny, Russia.
Eliseeva IA; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Makeev VJ; Sirius University of Science and Technology, Sochi, Russia.
Gladyshev VN; Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow, Russia.
Dmitriev SE; Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
Kulakovskiy IV; Max Perutz Labs, Medical University of Vienna, University of Vienna, Vienna, Austria.

Methods Mol Biol ; 2252: 269-294, 2021.

Article em En | MEDLINE | ID: mdl-33765281

Assuntos

Biologia Computacional/métodos; RNA Mensageiro/genética; Ribossomos/metabolismo; Animais; Sequenciamento de Nucleotídeos em Larga Escala; Humanos; Modelos Lineares; Distribuição de Poisson; Biossíntese de Proteínas; RNA Mensageiro/metabolismo; Análise de Sequência de RNA; Software

Palavras-chave

Linear regression; Polarity; Ribo-Seq; Ribosome distribution; Ribosome footprint coverage; Ribosome footprint density; Segmentation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribossomos / RNA Mensageiro / Biologia Computacional Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Methods Mol Biol Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Federação Russa

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