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Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication.
Guo, Haitao; Wang, Qi; Ghneim, Khader; Wang, Li; Rampanelli, Elena; Holley-Guthrie, Elizabeth; Cheng, Liang; Garrido, Carolina; Margolis, David M; Eller, Leigh A; Robb, Merlin L; Sekaly, Rafick-Pierre; Chen, Xian; Su, Lishan; Ting, Jenny P-Y.
Afiliação
  • Guo H; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Wang Q; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Ghneim K; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Wang L; Department of Pathology, Emory University, Atlanta, GA, USA.
  • Rampanelli E; Department of Biochemistry & Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Holley-Guthrie E; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Cheng L; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Garrido C; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Margolis DM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Eller LA; HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Robb ML; HIV Cure Center and Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
  • Sekaly RP; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Chen X; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Su L; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Ting JP; Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Nat Immunol ; 22(4): 423-433, 2021 04.
Article em En | MEDLINE | ID: mdl-33767427

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação Oxidativa / Replicação Viral / Linfócitos T CD4-Positivos / Infecções por HIV / HIV-1 / Proteoma / Genômica / Metaboloma / Metabolômica / Transcriptoma Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação Oxidativa / Replicação Viral / Linfócitos T CD4-Positivos / Infecções por HIV / HIV-1 / Proteoma / Genômica / Metaboloma / Metabolômica / Transcriptoma Limite: Animals / Female / Humans / Male Idioma: En Revista: Nat Immunol Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos