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Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research.
Yoo, Minjin; Park, Tae Hyun; Yoo, Miyoun; Kim, Yeongrin; Lee, Joo-Youn; Lee, Kyu Myung; Ryu, Seong Eon; Lee, Byung Il; Jung, Kwan-Young; Park, Chi Hoon.
Afiliação
  • Yoo M; Department of Medicinal Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Korea.
  • Park TH; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Korea.
  • Yoo M; Department of Bioengineering, Hanyang University, Seoul 04763, Korea.
  • Kim Y; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
  • Lee JY; Department of Medicinal Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Korea.
  • Lee KM; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
  • Ryu SE; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
  • Lee BI; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
  • Jung KY; Department of Bioengineering, Hanyang University, Seoul 04763, Korea.
  • Park CH; Research Institute, National Cancer Center, Goyang-si, Gyeonggi 10408, Korea.
Molecules ; 26(6)2021 Mar 17.
Article em En | MEDLINE | ID: mdl-33802888

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas de Ciclo Celular / Inibidores Enzimáticos / Isoquinolinas Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Proteínas de Ciclo Celular / Inibidores Enzimáticos / Isoquinolinas Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2021 Tipo de documento: Article