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Acetylcholine ameliorates colitis by promoting IL-10 secretion of monocytic myeloid-derived suppressor cells through the nAChR/ERK pathway.
Zheng, Wanwei; Song, Huan; Luo, Zhongguang; Wu, Hao; Chen, Lin; Wang, Yuedi; Cui, Haoshu; Zhang, Yufei; Wang, Bangting; Li, Wenshuai; Liu, Yao; Zhang, Jun; Chu, Yiwei; Luo, Feifei; Liu, Jie.
Afiliação
  • Zheng W; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Song H; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Luo Z; Biotherapy Research Center of Fudan University and Shanghai Engineering Technology Research Center of Intelligent Cancer Medicine, Shanghai 200032, China.
  • Wu H; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Chen L; Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Wang Y; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Cui H; Biotherapy Research Center of Fudan University and Shanghai Engineering Technology Research Center of Intelligent Cancer Medicine, Shanghai 200032, China.
  • Zhang Y; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.
  • Wang B; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Li W; Fosun Lead (Shanghai) Healthcare Technologies Co., Ltd., Shanghai 200437, China.
  • Liu Y; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Zhang J; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Chu Y; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Luo F; Department of Digestive Diseases, Huashan Hospital, Fudan University, Shanghai 200040, China.
  • Liu J; Biotherapy Research Center of Fudan University and Shanghai Engineering Technology Research Center of Intelligent Cancer Medicine, Shanghai 200032, China; yiweichu@fudan.edu.cn feifeiluo@fudan.edu.cn jieliu@fudan.edu.cn.
Proc Natl Acad Sci U S A ; 118(11)2021 03 16.
Article em En | MEDLINE | ID: mdl-33836585
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monócitos / Doenças Inflamatórias Intestinais / Acetilcolina / Receptores Nicotínicos / Interleucina-10 / Sistema Nervoso Entérico / MAP Quinases Reguladas por Sinal Extracelular / Células Supressoras Mieloides Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Monócitos / Doenças Inflamatórias Intestinais / Acetilcolina / Receptores Nicotínicos / Interleucina-10 / Sistema Nervoso Entérico / MAP Quinases Reguladas por Sinal Extracelular / Células Supressoras Mieloides Limite: Animals / Female / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos