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AMBRA1 regulates cyclin D to guard S-phase entry and genomic integrity.
Maiani, Emiliano; Milletti, Giacomo; Nazio, Francesca; Holdgaard, Søs Grønbæk; Bartkova, Jirina; Rizza, Salvatore; Cianfanelli, Valentina; Lorente, Mar; Simoneschi, Daniele; Di Marco, Miriam; D'Acunzo, Pasquale; Di Leo, Luca; Rasmussen, Rikke; Montagna, Costanza; Raciti, Marilena; De Stefanis, Cristiano; Gabicagogeascoa, Estibaliz; Rona, Gergely; Salvador, Nélida; Pupo, Emanuela; Merchut-Maya, Joanna Maria; Daniel, Colin J; Carinci, Marianna; Cesarini, Valeriana; O'sullivan, Alfie; Jeong, Yeon-Tae; Bordi, Matteo; Russo, Francesco; Campello, Silvia; Gallo, Angela; Filomeni, Giuseppe; Lanzetti, Letizia; Sears, Rosalie C; Hamerlik, Petra; Bartolazzi, Armando; Hynds, Robert E; Pearce, David R; Swanton, Charles; Pagano, Michele; Velasco, Guillermo; Papaleo, Elena; De Zio, Daniela; Maya-Mendoza, Apolinar; Locatelli, Franco; Bartek, Jiri; Cecconi, Francesco.
Afiliação
  • Maiani E; Cell Stress and Survival Unit, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Milletti G; Computational Biology Laboratory, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Nazio F; Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Holdgaard SG; Department of Biology, University of Rome 'Tor Vergata', Rome, Italy.
  • Bartkova J; Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Rizza S; Cell Stress and Survival Unit, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Cianfanelli V; Genome Integrity Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Lorente M; Division of Genome Biology, Department of Medical Biochemistry and Biophysics, Science for Life Laboratory, Karolinska Institute, Stockholm, Sweden.
  • Simoneschi D; Redox Biology Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Di Marco M; Cell Stress and Survival Unit, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • D'Acunzo P; Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Di Leo L; Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.
  • Rasmussen R; Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
  • Montagna C; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
  • Raciti M; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY, USA.
  • De Stefanis C; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY, USA.
  • Gabicagogeascoa E; Computational Biology Laboratory, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Rona G; Center for Dementia Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
  • Salvador N; Department of Psychiatry, New York University School of Medicine, New York, NY, USA.
  • Pupo E; Melanoma Research Team, Cell Stress and Survival Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Merchut-Maya JM; Brain Tumor Biology Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Daniel CJ; Redox Biology Group, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Carinci M; UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy.
  • Cesarini V; Institute of Sports Medicine Copenhagen, Department of Orthopedic Surgery, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
  • O'sullivan A; Cell Stress and Survival Unit, Center for Autophagy, Recycling and Disease (CARD), Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Jeong YT; Research Laboratories, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Bordi M; Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.
  • Russo F; Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
  • Campello S; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
  • Gallo A; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY, USA.
  • Filomeni G; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY, USA.
  • Lanzetti L; Department of Biochemistry and Molecular Biology, School of Biology, Complutense University, Madrid, Spain.
  • Sears RC; Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain.
  • Hamerlik P; Candiolo Cancer Institute, FPO - IRCCS, Turin, Italy.
  • Bartolazzi A; Genome Integrity Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Hynds RE; DNA Replication and Cancer Group, Genome Integrity Unit, Danish Cancer Society Research Center, Copenhagen, Denmark.
  • Pearce DR; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA.
  • Swanton C; Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Pagano M; Department of Medical Sciences, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.
  • Velasco G; Department of Pediatric Onco-Hematology and Cell and Gene Therapy, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
  • Papaleo E; Department of Biomedical Sciences, Institute of Translational Pharmacology, National Research Council of Italy (CNR), Rome, Italy.
  • De Zio D; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
  • Maya-Mendoza A; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY, USA.
  • Locatelli F; Howard Hughes Medical Institute, NYU Grossman School of Medicine, New York, NY, USA.
  • Bartek J; Department of Biochemistry and Molecular Pharmacology, NYU Grossman School of Medicine, New York, NY, USA.
  • Cecconi F; Laura and Isaac Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY, USA.
Nature ; 592(7856): 799-803, 2021 04.
Article em En | MEDLINE | ID: mdl-33854232
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fase S / Instabilidade Genômica / Proteínas Adaptadoras de Transdução de Sinal / Ciclina D Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fase S / Instabilidade Genômica / Proteínas Adaptadoras de Transdução de Sinal / Ciclina D Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nature Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Dinamarca País de publicação: Reino Unido