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Impact of variant-level batch effects on identification of genetic risk factors in large sequencing studies.
Wickland, Daniel P; Ren, Yingxue; Sinnwell, Jason P; Reddy, Joseph S; Pottier, Cyril; Sarangi, Vivekananda; Carrasquillo, Minerva M; Ross, Owen A; Younkin, Steven G; Ertekin-Taner, Nilüfer; Rademakers, Rosa; Hudson, Matthew E; Mainzer, Liudmila Sergeevna; Biernacka, Joanna M; Asmann, Yan W.
Afiliação
  • Wickland DP; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Ren Y; National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
  • Sinnwell JP; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Reddy JS; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Pottier C; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Sarangi V; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Carrasquillo MM; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Younkin SG; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Ertekin-Taner N; Department of Clinical Genomics, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Rademakers R; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Hudson ME; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Mainzer LS; Department of Neurology, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Biernacka JM; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, United States of America.
  • Asmann YW; National Center for Supercomputing Applications, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
PLoS One ; 16(4): e0249305, 2021.
Article em En | MEDLINE | ID: mdl-33861770
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Sequenciamento de Nucleotídeos em Larga Escala Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estudo de Associação Genômica Ampla / Sequenciamento de Nucleotídeos em Larga Escala Tipo de estudo: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Estados Unidos