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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Gormley, Mark; Yarmolinsky, James; Dudding, Tom; Burrows, Kimberley; Martin, Richard M; Thomas, Steven; Tyrrell, Jessica; Brennan, Paul; Pring, Miranda; Boccia, Stefania; Olshan, Andrew F; Diergaarde, Brenda; Hung, Rayjean J; Liu, Geoffrey; Legge, Danny; Tajara, Eloiza H; Severino, Patricia; Lacko, Martin; Ness, Andrew R; Davey Smith, George; Vincent, Emma E; Richmond, Rebecca C.
Afiliação
  • Gormley M; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Yarmolinsky J; Bristol Dental Hospital and School, University of Bristol, Bristol, United Kingdom.
  • Dudding T; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Burrows K; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Martin RM; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Thomas S; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Tyrrell J; Bristol Dental Hospital and School, University of Bristol, Bristol, United Kingdom.
  • Brennan P; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Pring M; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Boccia S; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Olshan AF; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Diergaarde B; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.
  • Hung RJ; National Institute for Health Research Bristol Biomedical Research Centre at the University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, United Kingdom.
  • Liu G; Bristol Dental Hospital and School, University of Bristol, Bristol, United Kingdom.
  • Legge D; National Institute for Health Research Bristol Biomedical Research Centre at the University Hospitals Bristol and Weston NHS Foundation Trust, University of Bristol, Bristol, United Kingdom.
  • Tajara EH; University of Exeter Medical School, RILD Building, RD&E Hospital, Exeter, United Kingdom.
  • Severino P; Genetic Epidemiology Group, World Health Organization, International Agency for Research on Cancer, Lyon, France.
  • Lacko M; Bristol Dental Hospital and School, University of Bristol, Bristol, United Kingdom.
  • Ness AR; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.
  • Davey Smith G; Department of Woman and Child Health and Public Health, Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
  • Vincent EE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, United States of America.
  • Richmond RC; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, and UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, United States of America.
PLoS Genet ; 17(4): e1009525, 2021 04.
Article em En | MEDLINE | ID: mdl-33886544

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de LDL / Inibidores de Hidroximetilglutaril-CoA Redutases / Pró-Proteína Convertase 9 / Carcinoma de Células Escamosas de Cabeça e Pescoço Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de LDL / Inibidores de Hidroximetilglutaril-CoA Redutases / Pró-Proteína Convertase 9 / Carcinoma de Células Escamosas de Cabeça e Pescoço Tipo de estudo: Clinical_trials / Etiology_studies / Observational_studies / Risk_factors_studies / Systematic_reviews Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos