The effects of gamma irradiation on the lymphoid organs of rainbow trout and subsequent susceptibility to fish pathogens.
Vet Immunol Immunopathol
; 18(2): 173-80, 1988 Mar.
Article
em En
| MEDLINE
| ID: mdl-3388762
ABSTRACT
Fish were irradiated with 60Co gamma rays at doses ranging from 10 to 50 Gy. Lethal doses were determined in fishes of different ages. For a given dose, fry and fingerlings were more susceptible than subadults. Whatever the irradiation dose was, the fish displayed a sharp decrease in blood leucocyte count. At the lowest doses, this acute leucopaenia was reversible. The cellular damage in the lymphoid organs was particularly obvious in the thymus. The depletion of lymphoid cells from immunocompetent organs decreased (viral hemorrhagic septicaemia, VHS) or increased (Y. ruckeri, A salmonicida) the susceptibility of trout to pathogens. The suppressive effect of radiation was age dependent. Irradiation appeared to be a reliable technique to detect asymptomatic carrier fish.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doenças dos Peixes
/
Imunidade Inata
/
Tecido Linfoide
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Vet Immunol Immunopathol
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
França