Transfer and scale-up of the manufacturing of orodispersible mini-tablets from a compaction simulator to an industrial rotary tablet press.

Lura, Ard; Elezaj, Valentinë; Kokott, Marcel; Fischer, Björn; Breitkreutz, Jörg

Lura, Ard; Elezaj, Valentinë; Kokott, Marcel; Fischer, Björn; Breitkreutz, Jörg.

Afiliação

Lura A; Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitaetsstr. 1, 40225 Duesseldorf, Germany. Electronic address: ard.lura@hhu.de.
Elezaj V; Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Kokott M; Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Fischer B; Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitaetsstr. 1, 40225 Duesseldorf, Germany.
Breitkreutz J; Institute of Pharmaceutics and Biopharmaceutics, Heinrich Heine University, Universitaetsstr. 1, 40225 Duesseldorf, Germany.

Int J Pharm ; 602: 120636, 2021 Jun 01.

Article em En | MEDLINE | ID: mdl-33895296

Assuntos

Excipientes; Criança; Composição de Medicamentos; Humanos; Pós; Comprimidos; Resistência à Tração

Palavras-chave

Compaction simulator; Direct compression; Functionalized excipients; Mini-tablets; Rotary tablet press; Scale-up

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Excipientes Limite: Child / Humans Idioma: En Revista: Int J Pharm Ano de publicação: 2021 Tipo de documento: Article País de publicação: Holanda

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