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Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget.
Mak, Shinghung; Li, Wenming; Fu, Hongjun; Luo, Jialie; Cui, Wei; Hu, Shengquan; Pang, Yuanping; Carlier, Paul R; Tsim, Karl Wahkeung; Pi, Rongbiao; Han, Yifan.
Afiliação
  • Mak S; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China.
  • Li W; Division of Life Science and Center for Chinese Medicine and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
  • Fu H; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, USA.
  • Luo J; Department of Neuroscience, Chronic Brain Injury, The Ohio State University, Columbus, OH, USA.
  • Cui W; Department of Anesthesiology, The Center for the Study of Itch and Sensory Disorders, Washington University School of Medicine, St. Louis, MO, USA.
  • Hu S; Zhejiang Provincial Key Laboratory of Pathophysiology, Ningbo Key Laboratory of Behavioral Neuroscience, School of Medicine, Ningbo University, Ningbo, China.
  • Pang Y; Shenzhen Institute of Geriatrics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China.
  • Carlier PR; Mayo Cancer Center, Department of Pharmacology, Mayo Clinic, Rochester, MN, USA.
  • Tsim KW; Department of Chemistry, Virginia Tech, Blacksburg, VA, USA.
  • Pi R; Shenzhen Key Laboratory of Edible and Medicinal Bioresources, HKUST Shenzhen Research Institute, Shenzhen, China.
  • Han Y; Division of Life Science and Center for Chinese Medicine and State Key Laboratory of Molecular Neuroscience, The Hong Kong University of Science and Technology, Hong Kong, China.
J Neurochem ; 158(6): 1381-1393, 2021 09.
Article em En | MEDLINE | ID: mdl-33930191

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Sesquiterpenos / Tacrina / Inibidores da Colinesterase / Sistemas de Liberação de Medicamentos / Doenças Neurodegenerativas / Alcaloides Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: J Neurochem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Acetilcolinesterase / Sesquiterpenos / Tacrina / Inibidores da Colinesterase / Sistemas de Liberação de Medicamentos / Doenças Neurodegenerativas / Alcaloides Tipo de estudo: Diagnostic_studies Limite: Animals / Humans Idioma: En Revista: J Neurochem Ano de publicação: 2021 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido