Acetaminophen Therapy for Persistent Patent Ductus Arteriosus.
Neoreviews
; 22(5): e320-e331, 2021 05.
Article
em En
| MEDLINE
| ID: mdl-33931477
ABSTRACT
Persistence of a left-to-right shunt caused by a patent ductus arteriosus (PDA) leads to significant sequelae in extremely premature infants as a result of pulmonary overcirculation and systemic steal. Although timing and duration of treatment for a persistent clinically significant PDA differ among institutions, standard pharmacologic interventions are the nonsteroidal anti-inflammatory drugs indomethacin and ibuprofen. Acetaminophen has emerged as an alternative to indomethacin and ibuprofen with less significant adverse effects, but there is no consensus regarding its use. This review summarizes the most recent evidence for the use of acetaminophen in PDA treatment.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Permeabilidade do Canal Arterial
/
Acetaminofen
Limite:
Humans
/
Newborn
Idioma:
En
Revista:
Neoreviews
Ano de publicação:
2021
Tipo de documento:
Article